What does the word 12 Lipoxygenase mean?

  • An enzyme that catalyzes the oxidation of arachidonic acid to yield 12- hydroperoxyarachidonate ( 12- HPETE) which is itself rapidly converted by a peroxidase to 12- hydroxy- 5, 8, 10, 14- eicosatetraenoate ( 12- HETE). The 12- hydroperoxides are preferentially formed in platelets. EC 1. 13. 11. 31.

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