What does the word Avian Sarcoma Virus Transforming Protein mean?
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A tyrosine- specific protein kinase encoded by the v- src oncogene of Rous sarcoma virus. The transforming activity of pp60( v- src) depends on both the lack of a critical carboxy- terminal tyrosine phosphorylation site at position 527, and the attachment of pp60( v- src) to the plasma membrane which is accomplished by myristylation of its N- terminal glycine. EC 2. 7. 11.-.
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