What does the word C1q mean?
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Subcomponent of complement 1 ( C1) which recognizes and binds to the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M initiating the classical complement pathway. The interaction of C1q and immunoglobulin activates C1r and C1s. The activated C1r and C1s molecules are cleaved off the complex by C1- inhibitor, allowing the collagen- like region of C1q to become accessible for interaction with cell membrane C1q receptors.
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